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Admissions to ICU occurred during weekends (Saturday and Sunday) in 1,708 (23%) cases, during the night (-) in 3,855 (52%), and on nights and/or weekends in 4,659 (63%) cases.Among 5,992 survivors to ICU discharge, 903 (15%) were discharged on weekends, 659 (11%) at night, and 1,434 (24%) on nights and/or weekends.BACKGROUND: Although the association between mortality and admission to intensive care units (ICU) in the "after hours" (weekends and nights) has been the topic of extensive investigation, the timing of discharge from ICU and outcome has been less well investigated.The objective of this study was to assess effect of timing of admission to and discharge from ICUs and subsequent risk for death.A weekend was Analysis was performed using Stata version 11.2 (Stata Corp, College Station, TX).To avoid the assessment of multiple outcomes for a single patient, only first ICU presentations were analyzed from patients with multiple ICU admissions.

According to French law, this study did not require individual patient consent, as it involved research on a previously developed and approved database.

METHODS: Adults (≥ 18 years) admitted to French ICUs participating in Outcomerea between January 2006 and November 2010 were included.

RESULTS: Among the 7,380 patients included, 61% (4,481) were male, the median age was 62 (IQR, 49-75) years, and the median SAPS II score was 40 (IQR, 28-56).

Once all of the admissions to ICU were identified fulfilling enrollment criteria, the following information were extracted for each patient at presentation: age and sex, admission category (medical, scheduled surgery, or unscheduled surgery).

Severity of illness was evaluated at presentation to ICU using the Simplified Acute Physiology Score (SAPS II) and sepsis-related organ failure assessment (SOFA) [12].

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Patients who suffer acute illness and are admitted during the "after hours" (weekends or nights) may be at higher risk for adverse outcome as compared to patients admitted during weekdays [1].

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